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美国贝勒医学院招聘神经内分泌博士后或访问学者
  2014-06-03  

A postdoctoral or visiting scholar position is available immediately at Baylor College of Medicine to investigate the neural control of feeding behavior and etiological mechanisms of obesity and eating disorders in genetic mouse models.

Hypothalamic AgRP neurons are critical for regulation of feeding and body weight, as acute ablation of these cells in adult mice leads to anorexia and profound weight loss . We demonstrated that such anorexic phenotype is fully reversible with the aid of a GABA-A receptor agonist and that GABA release from AgRP neurons onto neurons in the lateral parabrachial nucleus (PBN) is essential for maintenance of appetite and body weight . Furthermore, we identified a novel excitatory hindbrain circuit and associated signaling pathways that mediates appetite .

This newly established laboratory is fully funded and well equipped, which permits utilization of cutting-edge technologies including, conditional gene targeting, viral-based circuit mapping and gene transfer, optogenetics and chemogenetics, in vivo and ex vivo electrophysiology, calcium imaging, functional profiling of novel drug targets, and CLAMS for metabolic and behavioral analysis. In addition, Baylor College of Medicine has outstanding core research facilities (microscopy & imaging, genomic, proteomic and transgenic) for the rapid advancement of research work.

The ideal candidate will be a recent PhD and/or MD with a strong background in molecular biology and physiology. Ones who have direct hands-on experience in electrophysiology techniques would be much preferred. To apply send your CV with publication list, statement of research interests, and name & contact info of at least 3 referees to us fangxuezhuanjia@163.com

贝勒医学院(Baylor College of Medicine)是美国的一所私立医学院,被认为是全美最杰出的医学院之一。它坐落于德克萨斯州的休士顿,位于著名的德克萨斯医学中心里面。该校 1900年原成立于达拉斯,为达拉斯大学医学部,三年后依附于Waco的贝勒大学,并于1943年脱离贝勒大学而独立,并且搬移到休士顿,现在与贝勒大学是属于两个完全不同的学校。

贝勒医学院是全美少数资金超过十亿美金的学校之一,在USNEWS全美医学院排名当中,贝勒医学院于医学研究项目排在全美第十,临床治疗排在第十一,博士班排名二十二。双宇联合访问学者介绍贝勒医学院:全美能够在医学院,治疗部和生物研究三方面均进入前10%的机构仅有4家:贝勒医学院、杜克大学、加州大学旧金山分校以及华盛顿大学。贝勒医学院的研究强项在发育生物学,细胞生物学,心血管疾病以及干细胞研究。

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